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Hormone Therapy for Men: What You Need to Know About HRT Beyond Testosterone

Expanding HRT for Men in 2025

While Testosterone Replacement Therapy (TRT) gets thespotlight, many men can benefit from a broader hormone therapy approach.Estrogen balance, cortisol, DHEA, and thyroid function all play a role in howmen feel and perform.

How Does HRT Differ from TRT?

HRT for men may combine testosterone with estradiolregulation, thyroid hormone (T3/T4), or DHEA. As men age,these other hormones can decline too, leading to symptoms like brain fog, lowenergy, and poor recovery.

Hormones to Monitor:

  • Estradiol  (E2): Vital for joint health, libido, and heart protection.
  • Thyroid  (T3/T4): Controls metabolism, energy, and mental clarity.
  • DHEA:  Supports adrenal health and testosterone conversion.

Key Study:

  • Journal of Men's Health 2024: Men with combined hormone optimization (T + thyroid + DHEA) saw 30% improvement in cognitive function and 25%  better metabolic health.
  • Endocrine Reviews 2023: Men with balanced estradiol levels had lower  cardiovascular risks compared to those with too low or too high levels.

Why DirectCare AI?

We offer complete hormone panels for men and createindividualized treatment plans that go beyond just testosterone. Feel better,think clearer, and live healthier with full-spectrum HRT.